PsiAN – Psilocybin for Anorexia Nervosa
Anorexia nervosa is a serious eating disorder with one of the highest mortality rates in
psychiatry.

• Affects about 1% of teenage girls, often starting at 14 to 18 years of age.
• Relapse is common, and about 20% develop a severe, long-lasting form (SE-AN).
• No medicines are currently approved for treatment.

Psilocybin is a naturally occurring compound found in certain mushrooms. Clinical studies have shown promising results in conditions such as depression and addiction. It is thought to enhance brain flexibility by loosening rigid patterns of thought and behavior. The PsiAN study is testing whether psilocybin, combined with professional psychological support, can be a safe and helpful addition to treatment for anorexia nervosa.

• Where: University Hospital for Psychiatry, Lund
• Who: 40 participants aged 16–35
• How: Psilocybin + therapy + standard care vs. standard care alone
• Goal: First, to ensure safety. Second, to explore potential benefits

“This study is made possible through financial support from Norrsken Mind, Lund
University, and Region Skåne.”